The Mastermind orchestrates a series of bank robberies that are notable for their precise demands -- and their explosive violence when demands are not met excatly. Detective Alex Cross takes on the case and recognizes that a particular kind of criminal mind is at work. Cross's investigation gets under the Mastermind's skin, and he makes it his personal goal to take revenge on Cross and his entire team. Amidst all this, Cross's relationship with his girlfriend Christine is falling apart, and his beloved daughter Jannie is hospitalized with unexplained seizures. The pressure rises on every front, culminating in a shocking and explosive climax.