Riley and Clay are once again on the run from the Breeders. The group may have escaped the deranged experiments at the hospital, but as one of the world's last free women, Riley can never be safe. On the road back home, Riley and her crew are captured by a band of savage men. Their destination: the Citadel, run by a bizarre religious prophet named the Messiah. Somehow he knows their secrets. He wants them to join his group of Believers.